2023
Carlson PM, et al. “Radiation to all macroscopic sites of tumor permits greater systemic anti-tumor response to in situ vaccination,” Journal for ImmunoTherapy of Cancer;11:e005463. doi: 10.1136/jitc-2022-005463 (2023)
Allen KJH, Kwon O, Hutcheson MR, Grudzinski JJ, Cain SM, Cruz FA, Vinayakamoorthy RM, Sun YS, Fairley L, Prabaharan CB, Dickinson R, MacDonald-Dickinson V, Uppalapati M, Bednarz BP, Dadachova E. Image-Based Dosimetry in Dogs and Cross-Reactivity with Human Tissues of IGF2R-Targeting Human Antibody. Pharmaceuticals (Basel);16(7):979. doi: 10.3390/ph16070979. PMID: 37513891; PMCID: PMC10384855. (2023)
IR. Marsh*, C. Li, J. Grudzinski, J. Jeffery, C. Longhurst, D.P. Adam, R. Hernandez, J.P. Weichert, P.M. Harari, and B.P. Bednarz, “Targeting of Head and Neck Cancer by Radioiodinated CLR1404 in Murine Xenograft Tumor Models with Partial Volume Corrected Theranostic Dosimetry,” Cancer Biotherapy and Radiopharmaceuticals, doi: 10.1089/cbr.2022.0084. Online ahead of print. (2023)
D. Adam*, C.G. Hammer, J. Ziege Malyshev, W.S. Culberson, T.J. Bradshaw, J.J. Grudzinski, P.M. Harari, B. Bednarz, “Creation of waterproof, TLD probes for dose measurements to validate image-based radiopharmaceutical therapy dosimetry workflow,” Biomedical Engineering Express, DOI 10.1088/2057-1976/accf22 (2023)
Shaheen N*, Burdick R, Peña-Chávez R, Ulmschneider C, Yee J, Kurosu A, Rogus-Pulia N, Bednarz BP. Use of Deep Learning to Segment Bolus During Videofluoroscopic Swallow Studies. Biomed Phys Eng Express. Epub ahead of print. PMID: 37948874 (2023)Bednarz, Theranostics and Patient-Specific Dosimetry, Seminars in Radiation Oncology, INVITED, 33(3):317-326 (2023)
Mitra, C. Bhushan, S. Ghose, D. Mills, A. Patel, H. Chan, M. Tarasek, T. Foo , S. Wells, S. Jupitz*, B. Bednarz, C. Brace, J. Holmes, D. Yeo, “A hybrid deformable registration method to generate motion-compensated 3D virtual MRI for fusion with interventional real-time 3D ultrasound,” International Journal of Computer Assisted Radiology and Surgery, published ahead of print https://doi.org/10.1007/s11548-023-02833-1
Sodji QH, Forsberg MH, Cappabianca D, Kerr CP, Sarko L, Shea A, Adam DP*, Eickhoff JC, Ong IM, Hernandez R, Weichert J, Bednarz BP, Saha K, Sondel PM, Capitini CM, Morris ZS. Comparative Study of the Effect of Radiation Delivered by Lutetium-177 or Actinium-225 on Anti-GD2 Chimeric Antigen Receptor T Cell Viability and Functions. Cancers (Basel). 2023 Dec 30;16(1):191
Hoffman SLV*, Mixdorf JC, Kwon O*, Johnson TR, Makvandi M, Lee H, Aluicio-Sarduy E, Barnhart TE, Jeffery JJ, Patankar MS, Engle JW, Bednarz BP, Ellison PA. Preclinical studies of a PARP targeted, Meitner-Auger emitting, theranostic radiopharmaceutical for metastatic ovarian cancer. Nucl Med Biol. 2023 Jul-Aug;122-123:108368.
Sá AC, Barateiro A, Bednarz BP, Almeida P, Vaz P, Madaleno T. Corrigendum: Comparison of 3DCRT and IMRT out-of-field doses in pediatric patients using Monte Carlo simulations with treatment planning system calculations and measurements. Front Oncol. 2023 Oct 9;13:1293922. doi: 10.3389/fonc.2023.1293922. Erratum for: Front Oncol. 2022
2022
Keiss AP, Hobbs RF, Bednarz B., Knox SJ, Meredith R, Escorcia FE, ASTRO’s Framework for Radiopharmaceutical Therapy Curriculum Development for Trainees, Rad. Onc. Bio. Phys., published ahead of print March 20, https://doi.org/10.1016/j.ijrobp.2022.03.018 (2022)
Adam DP*, Grudzinski J., Bormett I., Cox BL, Marsh IR*, Bradshaw TJ, Harari P, Bednarz B., “Validation of Monte Carlo Iodine-131 radiopharmaceutical dosimetry workflow using a 3D printed anthropomorphic head and neck phantom,” Med. Phys. DOI: 10.1002/mp.15699 (2022)
Grudzinski, J.J.; Hall, L.T.; Cho, S.; Liu, G.; Traynor, A.; Lee, M.H.; Longino, M.; Pinchuk, A.; Jaskowiak, C.;Bednarz B.; Weichert, J.; Kuo, J.S. Clinical Imaging and Dosimetry of a Pan-Cancer Targeting Alkylphosphocholine Analog, [124I]I-NM404. Radiation, 2, 215-227 (2022)
Adam DP*, Bednarz B., Frigo S., “Static MLC transmission simulation using two-dimensional ray tracing,” J. Applied Clin Med Phys First published: 20 May 2022 https://doi.org/10.1002/acm2.13646 (2022)
Cravo Sa, A. Barateiro, Bednarz B., et al., “Comparison of 3DCRT and IMRT out-of-field doses in pediatric patients using Monte Carlo simulations with treatment planning system calculations and measurements,” Frontiers Oncol Aug 5;12:879167. doi: 10.3389/fonc.2022.879167 (2022)
Potluri H, et al, “Anti-Tumor Efficacy of 90Y-NM600 Targeted Radionuclide Therapy and PD-1 Blockade is Limited by Regulatory T Cells in Murine Prostate Tumors,” Journal for ImmunoTherapy of Cancer Aug;10(8):e005060. doi: 10.1136/jitc-2022-005060 (2022)
2021
Xiao, E. Roncali, R. Hobbs, S. St. James, B. Bednarz, S. Benedict, Y.Dewaraja, E. Frey et al, “Towards individualized voxel-level dosimetry for radiopharmaceutical therapy”, Int J Radiation Oncol Biol Phys; 109(4): 902-904, 2021 , https://doi.org/10.1016/j.ijrobp.2020.08.026
Matrosic, W. Culberson, A. Shepard, S. Jupitz, B. Bednarz, “3D Dosimetric Validation of Ultrasound-Guided Radiotherapy with a Dynamically Deformable Abdominal Phantom,” Physica Medica 84:159-167 (2021)
B. Bednarz, et al, “First-in-human Imaging Using a MR-compatible e4D ultrasound probe for motion management of radiation therapy,” Physica Medica Aug;88:104-110 (2021)
Patel R, Hernandez R, Carlson P, Grudzinski J, Bates A, Jagodinski J, Erbe A, Marsh I*, Aluicio-Sarduy E, Rakhmilevich A, Vail D, Engle J, Kim K, B. Bednarz, Sondel P, Weichert J, and Morris Z. “Low-dose targeted radionuclide therapy renders immunologically “cold” tumors responsive to immune checkpoint blockade.” Sci Transl Med 13, 602 (2021)
Magee, M.M. Turek, I. Marsh*, J. Grudzinski, E. Aluicio-Sarduy, J.W. Engle, I.D. Kurzman, C.L. Zuleger, E.A. Oseid, C. Jaskowiak, M.R. Albertini, B. Bednarz, P.M. Sondel, J.P. Weichert, Z.S. Morris, Reinier Hernandez, D.M. Vail, “Safety and feasibility of an in situ vaccination and theranostic targeted radionuclide combination immuno-radiotherapy approach in a comparative (companion dog) setting,” PLOS 16(8) (2021)
C. Jagodinsky, A. M. Bates, I. Chakravarty, I. S. Arthur, L. M. Zangl, R. J. Brown, E. J. Nystuen, S. E. Emma, C. Kerr, W.Jong Jin, P.M. Carlson, J. W Engle, E. Aluicio-Sarduy2, T.E. Barnhart, R. Hernandez, J.J. Grudzinski, I.R. Marsh*,B. Bednarz, J.P. Weichert, R.B. Patel, and Z.S. Morris, “Temporal analysis of type 1 interferon activation in tumor cells following external beam radiotherapy or targeted radionuclide therapy,” Theranostics 11(13): 6120-6137 (2021)
Clark PA, Sriramaneni RN, Bates AM, Jin WJ, Jagodinsky JC, Hernandez R, Le T, Jeffery JJ, Marsh IR*, Grudzinski JJ, Aluciocio-Sarduy E, Barnhart TE, Anderson BR, Chakravarty I, Arthur IS, Kyung-Mann K, Engle JW, B. Bednarz, Weichert JP, and Morris ZS. “Low dose radiation potentiates the propagation of anti-tumor immunity against melanoma tumor in the brain following in situ vaccination at a tumor outside the brain,” Radiat Res. Apr 7. doi: 10.1667/RADE-20-00237.1. Online ahead of print. (2021)
2020
E. Roncali, J. Capala, S. H Benedict, G. Akabani, B. Bednarz et al “Overview of the First NRG-NCI Workshop on Dosimetry of Systemic Radiopharmaceutical Therapy (RPT),” J Nucl Med jnumed.120.255547 published ahead of print December 4, 2020 (10.2967/jnumed.120.255547).
St James S, Bednarz B, Benedict S, et al. Current Status of Radiopharmaceutical Therapy [published online ahead of print, 2020 Aug 14]. Int J Radiat Oncol Biol Phys. 2020;S0360-3016(20)34125-0. doi:10.1016/j.ijrobp.2020.08.035
S. Jupitz, A. Shepard, P. Hill, B. Bednarz, “Investigation of Tumor and Vessel Correlation in the Liver,” J. App. Clin. Med. Phys. 21(8): 183-190 (2020)
M. E Bedir, B.P. Bednarz, B.R. Thomadsen, “Development and characterization of a handheld detector for radio-guided surgery,” Radiation Measurements 135: 106362 (2020)
Cravo Sa, A. Barateiro, B. Bednarz , et al., “Assessment of Out-of-Field Doses in Radiotherapy Treatments of Pediatric Patients using Monte Carlo Methods and Measurements,” Phys. Medica 71:53-61. (2020)
D. Adam, T. Liu, P. Caracappa, B. Bednarz, and X.G. Xu, “New capabilities of the Monte Carlo dose engine ARCHER-RT: clinical validation of the Varian TrueBeam machine for VMAT external beam radiotherapy,” Med Phys. 47(6):2537-2549. (2020)
B. Bednarz, et al, “First-in-human Imaging Using a MR-compatible e4D ultrasound probe for motion management of radiation therapy,” under review in Med. Phys. (2020)
C. Matrosic, B. Bednarz, and W. Culberson, “An Improved Abdominal Phantom for Intrafraction Image Guidance Validation” Phys. Med. Biol. 65(13): (2020)
2019
Marsh IR, Grudzinski JJ, Baiu DC, Besemer AE, Hernandez R, Jeffery JJ, Weichert JP, Otto M, B. Bednarz, “Preclinical pharmacokinetics and dosimetry studies of [124I/131I]-CLR1404 for treatment of pediatric solid tumors in murine xenograft models,” J Nucl Med, 60(10), 1414 (2019)
Grudzinski JJ, Hernandez R, Marsh I, Patel R, Aluicio-Sarduy E, Engle J, Morris Z, B. Bednarz, Weichert JP., Preclinical Characterization of 86/90Y-NM600 in a variety of murine and human cancer tumor models. J Nucl Med. 2019 Epub ahead of print PMID: 30954941
P. Ellison, A. Olson, T. Barnhart, S. Hoffman, S. Reilly, M. Makvandi, J. Burkemper, D. Murali, O. DeJesus, S. Lapi, B. Bednarz, R. Nickles, R.H. Mach, J. Engle, “Improved production of 76Br, 77Br and 80mBr via CoSe cyclotron targets and vertical dry distillation,” Nuclear Medicine and Biology, 80-81, 32 (2019)
C. Matrosic, J. Hull, B. Palmer, W. Culberson, and B. Bednarz, “Deformable Abdominal Phantom for the Validation of Real-Time Image Guidance and Deformable Dose Accumulation,” J. App. Clin. Med. Phys. 20(8), 122 (2019)
2018
C. Baiu, I. Marsh, A.E. Boruch, A.S. De, S. Bhattacharya, J. Jeffery, Q. Zhao, L. Hall, J. Weichert, B. Bednarz, M. Otto, “Targeted molecular radiotherapy of pediatric solid tumors using radioiodinated CLR1404 alkyl-phospholipid ether, J. Nuc. Med. 59(2), 244-250 (2018)
Y. Elsaid, E.A. Armstrong, A. Shahi, D.C. Baiu, S. Singhal, C. Li, L. Werner, L.T. Hall, J.P. Weichert, B. Bednarz, P.M. Harari, M. Otto, “Enhanced Radiosensitivity in Solid Tumors using a Tumor-Selective Alkyl Phospholipid Ether Analog,” Molecular Cancer Therapeutics 17(11), 2320-2328 (2018)
E. Besemer, Y. Yang, J.J. Grudzinski, L.T Hall, B. Bednarz, “Development and validation of RAPID: A patient-specific Monte Carlo 3D internal dosimetry platform,” Cancer Biother. Radiopharm. 3(4):155-165 (2018)
A. Shepard, C.K. Matrosic, J. Radtke, S.A. Jupitz*, W.S. Culberson, B. Bednarz, “Technical Note: Characterization of Clinical Linear Accelerator Triggering Latency for Motion Management System Development,” Med. Phys. 45(11) 4816-4821 (2018)
Besemer, J.J. Grudzinski, J. Weichert, L. Hall, B. Bednarz, “Pre-treatment CLR 124 PET accurately predicts CLR 131 3D dosimetry in triple negative breast cancer patient” Cancer Biother. Radiopharm 34(1), 13 (2018)
M. Matrosic, S. Holmes, B. Bednarz, W. Culberson, “Evaluation of a Clinical Dose Accumulation Algorithm using Deformable Gel Dosimetry,” Journal of Physics: Conference Series 1305 012002 (2018)
Lee D, Li M, B. Bednarz, and Schultz MK. Modeling Cell and Tumor-Metastasis Dosimetry with the Particle and Heavy Ion Transport Code System (PHITS) Software for Targeted Alpha-Particle Radionuclide Therapy. Rad Research Vol 190, No. 3 236-247 (2018)
2017
B. Bednarz and A. Besemer, “Radiation-Induced Second Cancer Risk Estimates from Radionuclide Therapy,” EPJ – Web Conf. 153 (2017)
Lin, T. Liu, L. Su, B. Bednarz, P.F. Caracappa, X.G. Xu, “Modeling of Radiotherapy Linac Source Terms Using ARCHER Monte Carlo Code: Performance Comparison for GPU and MIC Parallel Computing Devices,” EPJ – Web Conf. 153 (2017)
C. Matrosic, A. McMillan, J. Holmes, B. Bednarz, W. Culberson, “Dosimetric comparison of DEFGEL and PAGAT formulae paired with an MRI acquisition,” Journal of Physics: Conference Series 847, 012012, (2017)
S. Ellefson, W. Culberson, B. Bednarz, L. DeWerd, J. Bayouth, “A ViewRay-compatible corrections algorithm for the ArcCHECK-MR diode array,” Journal of Applied Clinical Medical Physics, 18 (4) (2017)
L. Hall, B. Titz, I. Robbins, S. Howard, B. Bednarz, S. Perlman, J. Weichert, J Kuo, “PET/CT Imaging of the Diapuetic Alkylphosphocholine Analog 124I-CLR1404 in High and Low-Grade Brain Tumors,” AJNMMI, 7(4) (2017)
A. Besemer, L. Hall, B. Titz, J. Grudzinski, J. Weichert, B. Bednarz, “Impact of PET and MRI threshold-based tumor volume segmentation on targeted radionuclide therapy patient-specific dosimetry using CLR1404,” 62 (15), 6008 Phys. Med. Bio. (2017)
A. Shepard, B. Wang, T. Foo, B. Bednarz, “A Shape-Based Learning Approach for Real-Time Ultrasound Tracking with Multiple Simultaneous Templates,” accepted in Med. Phys. (2017)
B. Bednarz, I. Marsh, J. Grudzinski, D.C. Baiu, A. Besemer, M. Otto, “Murine-specific internal dosimetry for preclinical investigations, 114(4), 450-458, Health Physics (2017)
W. Lee, H. Chan, P. Chan, T. Fiorillo, E. Fiveland, T. Foo, D. Mills, A. Patel, J. Sabatini, D. Shoudy, S. Smith, B. Bednarz, “A Magnetic Resonance Compatible E4D Ultrasound Probe for Motion Management of Radiation Therapy,” Published in IEEE International Ultrasonics Symposium (IUS) (2017)
S.F Kry, B. Bednarz, R.M. Howell, L.T. Dauer, D.S. Followill, E.E. Klein, H. Paganetti, B. Wang, C-S Wuu, X. G. Xu, “AAPM TG 158: Measurement and calculation of doses outside the treated volume from external-beam radiation therapy,” Med. Phys. 44 (10) (2017)
J. Grudzinski, B. Titz, M. Longino, K. Kozak, K. Lange, J. Larrabee, I. Marsh, J. Jeffery, B. Bednarz, “I-125-CLR1404 Auger electrons for the targeted radiotherapy of triple-negative breast cancer,” Cancer Biother. Radiopharm, 33(3), 87-95. (2017)
T.L. Fowler, A.M. Bailey, M.M. Fisher, B. Bednarz, and R.J. Kimple, “Biological validation of a high-throughput irradiator for in vitro assays,” PLoS ONE 12(12): e0189494. (2017)
2016
C. Matrosic, W. Culberson, B. Rosen, E. Madsen, G. Frank, B. Bednarz, “Initial characterization of a gel patch dosimeter for in vivo dosimetry,” Phys. Med. Biol., 61(10), N240-248 (2016)
M. Bouchlaka, K. Ludwig, J.W. Gordon, M.R. Olsen, M.P. Kutz, B. Bednarz, S. B. Fain, C. M. Capitini, “19F-MRI for monitoring human NK cells in vivo,” Oncoimmunology, 5(5), (2016)
Y.M. Yang, M. Svatos, C. Zankowski, B. Bednarz, “Concurrent Monte Carlo Transport and Fluence Optimization with Fluence Adjusted Scalable Transport Monte Carlo,” Med. Phys. 43, 3034, (2016)
2015
Y.M. Yang, M Geurts, J B Smilowitz, E Sterpin, and B. Bednarz, “Investigation of dose perturbations in clinical Tomotherapy® treatments due to an equilibrium magnetic field”, Med. Phys., 42(2), (2015)
T.L. Fowler, B. Bednarz, R.J. Kimple, “High-throughput detection of DNA double-strand breaks through image cytometry,” Biotechniques, 58(1), 37-39 (2015)
Brand, M. Iiada, A.P. Stein, K.L. Corrigan, C.M. Braverman, J. Coan, H.E. Pearson, H. Bahrar, T.L. Fowler, B. Bednarz, S. Saha, D. Yang, P.S. Gill, M.W. Lingen, V. Saloura, R. Salgia, R.J. Kimple, D.L. Wheeler, “AXL is a logical molecular target in head and neck squamous cell carcinoma,” Clin. Can. Res., 21(11):2601-12 (2015)
Z. Morris, J. P. Weichert, J. Saker, E. A. Armstrong, A. Besesmer, B. Bednarz, R. J. Kimple, P. M. Harari, “Therapeutic combination of radiolabeled CLR1404 with external beam radiation in head and neck cancer,” Published Online First 6/26/2015 Radiotherapy and Oncology, (2015)
K Cao, B. Bednarz, L.S. Smith, T.K. Foo, K.A. Patwardhan, “Respiration induced fiducial motion tracking in ultrasound using an extended SFA approach,” Proc. SPIE, Medical Imaging, 9419 (2015)
2014
T.L. Fowler, R.K. Fulkerson, J.A. Micka, R.J. Kimple, B. Bednarz, “A novel high-throughput irradiator for in vitro radiation sensitivity bioassays,” Phys. Med. Biol., 59(6), 1459-1470 (2014)
L. Su, Y.M. Yang, B. Bednarz, X. Du, T. Lu, W. J, E. Sterpin, X.G. Xu, “ARCHERRT – A GPU-based and photon-electron coupled Monte Carlo dose computing engine for radiation therapy: Software development and application to helical tomotherapy,” Med. Phys., 41, 071709-1 (2014)
2013
Y.M. Yang and B. Bednarz, “Consistency evaluation between EGSnrc and Geant4 charged particle transport in an equilibrium magnetic field for clinical use,” Phys. Med. Biol. 58, N47-N58 (2013)
A Besemer, H. Paganetti, B. Bednarz, “Clinical impact of uncertainties in the mean excitation energy of human tissues during proton therapy,” Phys. Med. Biol. 58, 887-902 (2013)